Spike Trimer (S1+S2) (B.1.1.529 BA.1, Omicron Variant), His-Tag (SARS-CoV-2) Recombinant

• Description:

  Recombinant SARS-CoV-2 Spike protein in its homotrimeric form, containing S1+S2 subunits and encompassing amino acids 16-1213. This protein corresponds to SARS-CoV-2 Variant B.1.1.529 BA.1 also known as variant Omicron originally identified in South Africa, and contains Omicron Spike mutations listed below. The construct also contains mutations 682RRAR685>A, K986P and V987P, and a T4 trimerization domain followed by a His-tag (6xHis) in C-terminal. The recombinant protein was affinity purified.

• UniProt:

  P0DTC2

• Tag:

  C-terminal His-tag

• Applications:

  Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

• Purity:

  80%

• Format:

  Aqueous buffer solution

• Shipping Conditions:

  -80°C

• Storage Conditions:

  At least 6 months at -80°C.

• Calculated Molecular Weight:

  137 kDa + glycans

• Formulation:

  8 mM phosphate pH 7.4,110 mM NaCl, 2.2 mM KCl, 20% glycerol

• Glycosylation:

  This protein runs at a higher MW by SDS-PAGE due to glycosylation.