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C-Raf Kinase Assay Kit

CAT: 0421-79570Size: 96 ReactionsDry Ice: YesHazardous: No
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CAT#:0421-79570Size:96 Reactions
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Description
C-Raf (Raf-1; proto-oncogen c-Raf) is a member of the Raf (rapidly accelerated fibrosarcoma) kinase family that plays an important role in regulating the MEK and ERK pathways. The c-Raf Kinase Assay Kit is designed for measuring c-Raf activity for screening and profiling applications.Need us to run inhibitor screens or profile your compounds against c-Raf? Check out ourKinase Screening Services.
UniProt
P04049
Format
Catalog NumberReagentAmountStorage40008c-Raf5 µg-80°CAvoid freeze/thawcycles!793345x Kinase assay buffer1.5 ml-20°C79686ATP (500 µM) 100 µl-20°C795695X Raf substrate1 ml-80°C7969696-well plate, white1Room Temp.
Shipping Conditions
-80°C
Storage Conditions
Up to 6 months when stored as recommended.

UniProtKB · P04049

RAF proto-oncogene serine/threonine-protein kinase

RAF1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P04049
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
RAF1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.11.1
Processing
—
Secondary accessions
B0LPH8, B2R5N3, Q15278, Q9UC20
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingMetal-bindingNucleotide-bindingZinc

Disease

CardiomyopathyDeafnessDisease variantProto-oncogene

Cellular component

Cell membraneCytoplasmMembraneMitochondrionNucleus

Molecular function

KinaseSerine/threonine-protein kinaseTransferase

PTM

MethylationPhosphoprotein

Domain

Zinc-finger