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FTO, His-Tag Recombinant

CAT: 0421-79306Size: 100 µgDry Ice: YesHazardous: No
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CAT#:0421-79306Size:100 µg
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Description
Recombinant human FT0 (alpha-ketoglutarate dependent dioxygenase FTO), encompassing amino acids 33-505 (end) . This construct contains an N-Terminal His-tag (6xHis) . The recombinant protein was affinity purified.
UniProt
Q9C0B1
Tag
N-Terminal His-Tag
Applications
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Purity
≥ 90%
Format
Aqueous buffer solution
Shipping Conditions
-80°C
Storage Conditions
At least 6 months at -80°C.
Calculated Molecular Weight
56 kDa
Formulation
40 mM Tris, pH 8.0,110 mM NaCl, 2.2 mM KCl, 20% glycerol, and 3 mM DTT

UniProtKB · Q9C0B1

Alpha-ketoglutarate-dependent dioxygenase FTO

FTO_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9C0B1
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
FTO
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A2RUH1, B2RNS0, Q0P676, Q7Z785
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmNucleus

Molecular function

DioxygenaseOxidoreductaseTransferase

Disease

Disease variantObesity

Ligand

IronMetal-binding

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