FR 75513
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- Dry Ice Shipment: No


FR 75513
Description:
FR 75513 is a 1,1'-biphenyl-2,6-dicarboxylic acid diester series compound that can inhibit the contraction of the detrusor muscle of guinea pig bladder (IC50=3.3 μg/mL) . After intravenous injection of FR 75513 into anesthetized rats, it also showed strong inhibitory activity on the detrusor contraction (ID50=0.04 mg/kg) .UNSPSC:
12352005Target:
Biochemical Assay ReagentsType:
Reference compoundRelated Pathways:
OthersApplications:
Neuroscience-NeuromodulationField of Research:
Neurological DiseaseAssay Protocol:
https://www.medchemexpress.com/fr-75513.htmlSmiles:
O=C(C1=C(C=C(C)C(C(OC(C)C)=O)=C1C2=C([N+]([O-])=O)C=CC=C2)O)OCMolecular Formula:
C19H19NO7Molecular Weight:
373.36References & Citations:
[1]Agents for the Treatment of Overactive Detrusor. I. Synthesis and Structure-Activity Relationships of 1, 1'-Biphenyl DerivativesShipping Conditions:
Room temperatureScientific Category:
Reference compound1Clinical Information:
No Development ReportedCAS Number:
[127975-78-4]
