(S, S) -TAPI-0

• Description:

  (S, S) -TAPI-0 is a matrix metalloproteinase (MMP) inhibitor that inhibits the growth of Chlamydia trachomatis by inhibiting PDF enzyme activity. (S, S) -TAPI-0 can be used to study Chlamydia infection[1].

• UNSPSC:

  12352005

• Target:

  MMP

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/s-s-tapi-0.html

• Smiles:

  C[C@@H](C(N)=O)NC([C@H](CC1=CC=C2C=CC=CC2=C1)NC(C(CC(NO)=O)CC(C)C)=O)=O

• Molecular Formula:

  C24H32N4O5

• Molecular Weight:

  456.53

• References & Citations:

  [1]Balakrishnan, et al. Metalloprotease inhibitors GM6001 and TAPI-0 inhibit the obligate intracellular human pathogen Chlamydia trachomatis by targeting peptide deformylase of the bacterium. Journal of Biological Chemistry 281.24 (2006) : 16691-16699.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [143457-40-3]