(S, S) -TAPI-0

• Description :

  (S, S) -TAPI-0 is a matrix metalloproteinase (MMP) inhibitor that inhibits the growth of Chlamydia trachomatis by inhibiting PDF enzyme activity. (S, S) -TAPI-0 can be used to study Chlamydia infection[1].

• UNSPSC :

  12352005

• Target :

  MMP

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/s-s-tapi-0.html

• Smiles :

  C[C@@H](C(N)=O)NC([C@H](CC1=CC=C2C=CC=CC2=C1)NC(C(CC(NO)=O)CC(C)C)=O)=O

• Molecular Formula :

  C24H32N4O5

• Molecular Weight :

  456.53

• References & Citations :

  [1]Balakrishnan, et al. Metalloprotease inhibitors GM6001 and TAPI-0 inhibit the obligate intracellular human pathogen Chlamydia trachomatis by targeting peptide deformylase of the bacterium. Journal of Biological Chemistry 281.24 (2006) : 16691-16699.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [143457-40-3]