Mulberroside A

• Description:

  Mulberroside A is one of the main bioactive constituent in mulberry (Morus alba L.) [1]. Mulberroside A decreases the expressions of TNF-α, IL-1β, and IL-6 and inhibits the activation of NALP3, caspase-1, and NF-κB and the phosphorylation of ERK, JNK, and p38, exhibiting anti-inflammatory antiapoptotic effects[2]. Mulberroside A shows inhibitory activity against mushroom tyrosinase with an IC50 of 53.6 μM[3].

• UNSPSC:

  12352005

• Hazard Statement:

  H315, H319

• Target:

  Interleukin Related; TNF Receptor; Tyrosinase

• Type:

  Natural Products

• Related Pathways:

  Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/Mulberroside-A.html

• Purity:

  99.92

• Solubility:

  DMSO : 50 mg/mL (ultrasonic)

• Smiles:

  O[C@H]([C@@H](O)[C@@H]1O)[C@@H](O[C@@H]1CO)OC2=CC(/C=C/C(C=CC(O[C@@H]([C@@H]([C@@H](O)[C@@H]3O)O)O[C@@H]3CO)=C4)=C4O)=CC(O)=C2

• Molecular Formula:

  C26H32O14

• Molecular Weight:

  568.52

• Precautions:

  H315, H319

• References & Citations:

  Morus alba

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• Isoform:

  IL-1; IL-6; TNFRSF5/CD40

• CAS Number:

  [102841-42-9]