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Sinulatumolin E

CAT: 0804-HY-N10448Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-N10448Size:1 Each
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Description
Sinulatumolin E (compound 6), a terpenoid, displays significant TNF-α inhibitory activity with an IC50 of 3.6 μM. Sinulatumolin E (compound 6) exhibits anti-inflammatory activity[1].
CAS Number
2570255-85-3
UNSPSC
12352211
Target
TNF Receptor
Type
Natural Products
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/sinulatumolin-e.html
Solubility
10 mM in DMSO
Smiles
C[C@]12C(CCC([C@H](/C(C)=C\2)O)=O)=CCC[C@@H]1C
Molecular Formula
C15H22O2
Molecular Weight
234.33
References & Citations
[1]Cai YS, et al. Uncommon terpenoids with anti-inflammatory activity from the Hainan soft coral Sinularia tumulosa. Bioorg Chem. 2020 Nov;104:104167.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
TNFRSF5/CD40

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