Carboxy finasteride

• UNSPSC Description:

  Carboxy finasteride is a metabolite of the 5α-reductase inhibitor Finasteride (HY-13635). Finasteride is biotransformed by cytochrome P450 (CYP3A4) and is successively oxidized to Hydroxy finasteride and Carboxy finasteride. Carboxy finasteride is the major metabolite in urine, while Hydroxy finasteride is the major metabolite in plasma[1].

• Target Antigen:

  Aldose Reductase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  cancer

• Assay Protocol:

  https://www.medchemexpress.com/carboxy-finasteride.html

• Smiles:

  C[C@@]12[C@](CC[C@@H]2C(NC(C)(C)C(O)=O)=O)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4([C@@](NC(C=C4)=O)([H])CC3)C

• Molecular Weight:

  402.53

• References & Citations:

  [1]The effect of St. John’s wort on the pharmacokinetics, metabolism and biliary excretion of finasteride and its metabolites in healthy men

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  116285-37-1