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Carboxy finasteride

CAT: 0804-HY-W739812-01Size: 2.5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W739812-01Size:2.5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Carboxy finasteride is a metabolite of the 5α-reductase inhibitor Finasteride. Finasteride is biotransformed by cytochrome P450 (CYP3A4) and is successively oxidized to Hydroxy finasteride and Carboxy finasteride. Carboxy finasteride is the major metabolite in urine, while Hydroxy finasteride is the major metabolite in plasma[1].
CAS Number
116285-37-1
Product Name Alternative
Finasteride carboxylic acid
UNSPSC
12352005
Target
Aldose Reductase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/carboxy-finasteride.html
Smiles
C[C@@]12[C@](CC[C@@H]2C(NC(C)(C)C(O)=O)=O)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4([C@@](NC(C=C4)=O)([H])CC3)C
Molecular Formula
C23H34N2O4
Molecular Weight
402.53
References & Citations
[1]The effect of St. John’s wort on the pharmacokinetics, metabolism and biliary excretion of finasteride and its metabolites in healthy men
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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