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Dusquetide

CAT: 0804-HY-P2076-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P2076-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Dusquetide (SGX942) is a first-in-class innate defense regulator (IDR) . Dusquetide modulates the innate immune response to both PAMPs and DAMPs by binding to p62. Dusquetide shows activity in both reducing inflammation and increasing clearance of bacterial infection[1]. DAMPs: damage-associated molecular patterns; PAMPs: pathogen-associated molecular patterns
CAS Number
931395-42-5
Product Name Alternative
SGX942
UNSPSC
12352209
Target
Bacterial; p62
Type
Peptides
Related Pathways
Anti-infection; Autophagy
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/dusquetide.html
Purity
99.96
Solubility
H2O : 50 mg/mL (ultrasonic)
Smiles
C[C@@H](C(N)=O)NC([C@H]1N(C([C@H](C(C)C)NC([C@H]([C@@H](C)CC)NC([C@H](CCCNC(N)=N)N)=O)=O)=O)CCC1)=O
Molecular Formula
C25H47N9O5
Molecular Weight
553.70
References & Citations
[1]Kudrimoti M, et al. Dusquetide: A novel innate defense regulator demonstrating a significant and consistent reduction in the duration of oral mucositis in preclinical data and a randomized, placebo-controlled phase 2a clinical study. J Biotechnol. 2016 Dec 10;239:115-125.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
Scientific Category
Peptides
Clinical Information
Phase 3

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