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Recombinant MSH6 Antibody

CAT: 0800-V9182-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-V9182-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MSH6 is a mismatch repair protein which is deficient in a high proportion of patients with microsatellite instability (MSI-H) .
CAS Number
9000-83-3
Specifications
ELISA (order BSA-free format for coating), Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
P52701
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 1-100 was used as the immunogen for the recombinant MSH6 antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG
Clone
MSH6/6654R
Type
Recombinant
Applications
ELISA, WB, IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the recombinant MSH6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This recombinant MSH6 antibody is available for research use only.
Storage Conditions
Aliquot the recombinant MSH6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the recombinant MSH6 antibody should be determined by the researcher.
Location
Nuclear
Image Legend
IHC staining of FFPE human colon carcinoma tissue with recombinant MSH6 antibody (clone MSH6/6654R) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.

UniProtKB · P52701

DNA mismatch repair protein Msh6

MSH6_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P52701
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MSH6
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
hMSH6
EC number
—
Processing
—
Secondary accessions
B4DF41, B4E3I4, F5H2F9, O43706, O43917, Q8TCX4, Q9BTB5
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingNucleotide-binding

Cellular component

ChromosomeNucleus

Disease

Disease variantHereditary nonpolyposis colorectal cancer

Biological process

DNA damageDNA repairHost-virus interaction

Molecular function

DNA-binding
Product Datasheet
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