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Recombinant SYP Antibody / Synaptophysin

CAT: 0800-V9154SAF-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-V9154SAF-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This Monoclonal antibody recognizes a protein of 38kDa that is identified as Synaptophysin. It is an N-glycosylated integral membrane protein found in neurons and endocrine cells. Synaptophysin contains four transmembrane domains and may function as a gap junction-like channel. This antibody identifies normal neuroendocrine cells and neuroendocrine neoplasms. Diffuse, finely granular, cytoplasmic staining is observed, which probably correlates with the distribution of the antigen within neurosecretory vesicles. Synaptophysin is an independent, broad-range marker of neural and neuroendocrine differentiation.
CAS Number
9000-83-3
Specifications
Immunohistochemistry (FFPE) : 2-4 µg/mL
UniProt
P08247
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 224-313 was used as the immunogen for the recombinant SYP antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG1 k
Clone
RSYP/6856
Type
Recombinant
Applications
IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Aliquot the recombinant SYP antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This recombinant SYP antibody is available for research use only.
Storage Conditions
Aliquot the recombinant SYP antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Optimal dilution of the recombinant SYP antibody should be determined by the researcher.
Location
Cytoplasm
Image Legend
IHC staining of FFPE human brain tissue with recombinant SYP antibody (clone rSYP/6856) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
Product Datasheet
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