Products for Research Use Only

RBMS2 Antibody / SCR3

CAT: 0800-V8997SAF-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-V8997SAF-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RBMS2 is a member of a small family of proteins that bind single stranded DNA or RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, and are required for DNA binding. The RBMS proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. RBMS2 (RNA-binding motif, single-stranded-interacting protein 2) is a 407 amino acid protein that contains 2 RRM (RNA recognition motif) domains and localizes to nucleus. It has been suggested that RBMS2 suppresses Cdc2 kinase and Cdc13 cyclin mutants through the induction of translation of Cdc2. The RBMS2 gene is conserved in chimpanzee, canine, bovine, mouse, rat and zebrafish, and maps to human chromosome 12q13.3.
CAS Number
9007-83-4
Specifications
ELISA (For coating, order BSA-free format), Immunoprecipitation: 1-2ug per 100-500ug of total protein (1ml of cell lysate), Flow cytometry: 1-2ug/million cells
UniProt
Q15434
Host
Mouse
Reactivity
Human
Immunogen
Recombinant full-length human RBMS2 protein was used as the immunogen for the RBMS2 antibody.
Clonality
Monoclonal
Isotype
IgG1
Clone
PCRP-RBMS2-1B6
Applications
ELISA, IP, FACS
Purity
Protein A/G affinity
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Aliquot the RBMS2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This RBMS2 antibody is available for research use only.
Storage Conditions
Aliquot the RBMS2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Optimal dilution of the RBMS2 antibody should be determined by the researcher.
Location
Nucleus, Cytoplasm
Image Legend
FACS staining of PFA-fixed human HeLa cells with RBMS2 antibody (blue, clone PCRP-RBMS2-1B6) and isotype control (red) .

UniProtKB · Q15434

RNA-binding motif, single-stranded-interacting protein 2

RBMS2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q15434
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
RBMS2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
—
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Cellular component

Nucleus

Domain

Repeat

Molecular function

RNA-binding