RBMS2 Antibody / SCR3

CAT: 0013-GTR18571687Size: 100 µgDry Ice: NoHazardous: No

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CAT#:0013-GTR18571687Size:100 µg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

RBMS2 is a member of a small family of proteins that bind single stranded DNA or RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, and are required for DNA binding. The RBMS proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. RBMS2 (RNA-binding motif, single-stranded-interacting protein 2) is a 407 amino acid protein that contains 2 RRM (RNA recognition motif) domains and localizes to nucleus. It has been suggested that RBMS2 suppresses Cdc2 kinase and Cdc13 cyclin mutants through the induction of translation of Cdc2. The RBMS2 gene is conserved in chimpanzee, canine, bovine, mouse, rat and zebrafish, and maps to human chromosome 12q13.3.

UniProt

Q15434

Reactivity

Human

Immunogen

Recombinant full-length human RBMS2 protein was used as the immunogen for the RBMS2 antibody.

Clonality

Monoclonal

Clone

PCRP-RBMS2-1B6

Conjugation

Unconjugated

Purification

Protein A/G affinity

Dilution

ELISA (For coating, order BSA-free format), Immunoprecipitation: 1-2ug per 100-500ug of total protein (1ml of cell lysate), Flow cytometry: 1-2ug/million cells

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

Optimal dilution of the RBMS2 antibody should be determined by the researcher.

Tested Applications

ELISA, FACS, IP

Host or Source

Mouse

Preservative

1 mg/ml in 1X PBS; rAlbumin free, sodium azide free

Isotype

Mouse IgG1

UniProtKB · Q15434

RNA-binding motif, single-stranded-interacting protein 2

RBMS2_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q15434
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: RBMS2
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: —
Processing: —
Secondary accessions: —

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Cellular component

Nucleus

Domain

Repeat

Molecular function

RNA-binding

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Alternative Products

Catalog	Name
V8997-20UG	RBMS2 Antibody / SCR3
513530	RBMS2 (SCR3) discontinued
588672	RBMS2 (FLJ39093, FLJ40023, FLJ43262, SCR3)
70R-19820	RBMS2 antibody
040904	RBMS2, NT (RBMS2, SCR3, RNA-binding motif, single-stranded-interacting protein 2, Suppressor of CDC2 with RNA-binding motif 3)