Products for Research Use Only
RegisterLogin

IL3RA Antibody / CD123

CAT: 0800-V8952-20UGSize: 20 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-V8952-20UGSize:20 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
CD123 is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5) . The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudo-autosomal region on chromosomes X or Y.
CAS Number
9007-83-4
Specifications
ELISA: 2-4 µg/mL (order BSA-free format for coating)
UniProt
P26951
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 26-171 was used as the immunogen for the IL3RA antibody.
Clonality
Monoclonal
Isotype
IgG2a κ
Clone
IL3RA/2065
Applications
ELISA
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the IL3RA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This IL3RA antibody is available for research use only.
Storage Conditions
Aliquot the IL3RA antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the IL3RA antibody should be determined by the researcher.
Location
Cell surface and cytoplasm
Image Legend
Analysis of HuProt (TM) microarray containing more than 19,000 full-length human proteins using IL3RA antibody (clone IL3RA/2065) . These results demonstrate the foremost specificity of the IL3RA/2065 mAb. Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt (TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt (TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.

UniProtKB · P26951

Interleukin-3 receptor subunit alpha

IL3RA_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P26951
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
IL3RA
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
IL-3 receptor subunit alpha, IL-3R subunit alpha, IL-3R-alpha, IL-3RA
EC number
—
Processing
Precursor
Secondary accessions
A8K3F3, B9VI81, Q5HYQ7, Q5HYQ8, Q9UEH7
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneMembrane

PTM

Disulfide bondGlycoproteinUbl conjugation

Molecular function

Receptor

Domain

SignalTransmembraneTransmembrane helix

Related Products

CatalogName
V7291IHC-7MLCD123 Antibody / IL3RA
R35737-100UGCD123 Antibody / IL3RA
V7291SAF-100UGCD123 Antibody / IL3RA
V7291-20UGCD123 Antibody / IL3RA
V7291-100UGCD123 Antibody / IL3RA
RQ5983CD123 Antibody / IL3RA
V7426-100UGRecombinant CD123 Antibody / IL3RA
V7426SAF-100UGRecombinant CD123 Antibody / IL3RA
V7426IHC-7MLRecombinant CD123 Antibody / IL3RA
V7426-20UGRecombinant CD123 Antibody / IL3RA

Alternative Products

CatalogName
GTR18223751IL3RA/CD123 Antibody
GTR18574325CD123 Antibody / IL3RA
43-665IL3RA / CD123 Antibody
MBS1753105-01Anti-IL3RA/CD123 Antibody
ANT-10717-100ugCD123 / IL3RA Monoclonal Antibody
STJ73126Anti-IL3RA / CD123 antibody
GTR18574968Recombinant IL3RA Antibody / CD123
GTR18574536Recombinant CD123 Antibody / IL3RA
GTR18776586-01Human CD123/IL3RA Antibody
ANT-10718-100ugCD123 / IL3RA Polyclonal Antibody

Popular Products