MERTK Antibody

• Description :

  MERTK, also called c-Mer, is a member of the Mer/Axl/Tyro3 receptor kinase family. It protein plays a critical role in macrophage activation, platelet aggregation, clot stability and the efficient removal of apoptotic cells.

• Specifications :

  Immunohistochemistry (FFPE) : 1-2 µg/mL

• UniProt :

  Q12866

• Host :

  Mouse

• Reactivity :

  Human

• Immunogen :

  A portion of amino acids 55-148 was used as the immunogen for the MERTK antibody.

• Clonality :

  Monoclonal

• Isotype :

  IgG2a

• Clone :

  MERTK/3023

• Applications :

  IHC-P

• Purity :

  Protein A/G affinity

• Format :

  Purified

• Buffer :

  0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

• Reconstitution :

  Aliquot the MERTK antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations :

  This MERTK antibody is available for research use only.

• Storage Conditions :

  Aliquot the MERTK antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation :

  0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide

• Applications Notes :

  Optimal dilution of the MERTK antibody should be determined by the researcher.

• CAS Number :

  9007-83-4

• Location :

  Cell surface

• Image Legend :

  IHC staining of FFPE human colon carcinoma tissue with MERTK antibody (clone MERTK/3023) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.