Products for Research Use Only
RegisterLogin

Recombinant ACTH Antibody (Synacthen)

CAT: 0800-V8807-20UGSize: 20 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-V8807-20UGSize:20 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
ACTH (same as Corticotropin) is a 39 amino acid active peptide produced by the anterior pituitary. This MAb is specific to Synacthen (aa1-24 of ACTH) ; does not react with CLIP (aa17-39 of ACTH) . POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive, tissue-specific posttranslational processing by convertases. POMC is cleaved into ten hormone chains named NPP, ACTH, alpha-MSH (Melanocyte Stimulating Hormone), beta-MSH, gamma-MSH, CLIP (corticotropin-like intermediary peptide), Lipotropin-beta, Lipotropin-gamma, beta-endorphin and Met-enkephalin.
CAS Number
9000-83-3
Specifications
ELISA (For coating order BSA-free format), Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
P01189
Host
Mouse
Reactivity
Human, Mouse, Rat
Immunogen
A recombinant protein fragment from the N-terminal region of human ACTH was used as the immunogen for the recombinant ACTH antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG1 k
Clone
RCLIP/3814
Type
Recombinant
Applications
ELISA, IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the recombinant ACTH antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This recombinant ACTH antibody is available for research use only.
Storage Conditions
Aliquot the recombinant ACTH antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the recombinant ACTH antibody should be determined by the researcher.
Location
Cytoplasm, Secreted
Image Legend
IHC staining of FFPE human pituitary gland tissue with recombinant ACTH antibody (clone rCLIP/3814) at 2ug/ml. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.

UniProtKB · P01189

Pro-opiomelanocortin

COLI_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P01189
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
POMC
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
POMC
EC number
—
Processing
Precursor
Secondary accessions
P78442, Q53T23, Q9UD39, Q9UD40
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationAmidationCleavage on pair of basic residuesDisulfide bondGlycoproteinPhosphoprotein

Molecular function

EndorphinHormone

Disease

Obesity

Cellular component

Secreted

Domain

Signal

Related Products

CatalogName
V2230SAF-100UGACTH Antibody / Synacthen
V2232SAF-100UGACTH Antibody / Synacthen
V2232-20UGACTH Antibody / Synacthen
V2230-20UGACTH Antibody / Synacthen
V4894-100UGACTH Antibody / Synacthen
V4894SAF-100UGACTH Antibody / Synacthen
V4894-20UGACTH Antibody / Synacthen
V2232-100UGACTH Antibody / Synacthen
V2230-100UGACTH Antibody / Synacthen
V3176SAF-100UGACTH Antibody Cocktail / Synacthen

Alternative Products

CatalogName
GTR18572050ACTH Antibody / Synacthen
bsm-60798RACTH Recombinant Antibody
GTR18082756-01Recombinant CLIP Antibody / ACTH
AN301965L-01Recombinant ACTH Monoclonal Antibody
GTR18573548Recombinant ACTH Antibody / CLIP
33-810Recombinant ACTH Antibody [r57]
MBS566831-01ACTH Recombinant monoclonal antibody (r57)
bsm-60798R-Cy3ACTH Recombinant Antibody, Cy3 Conjugated
bsm-60798R-RBITCACTH Recombinant Antibody, RBITC Conjugated
bsm-60798R-Cy5ACTH Recombinant Antibody, Cy5 Conjugated

Popular Products