CD46 Antibody

• Description:

  CD46 exists as many isoforms in a variety of tissues. It is strongly expressed on salivary gland ducts and kidney ducts, moderately on lymphocytes and endothelium, and weakly on interstitial tissues and muscle cells, but not on erythrocytes. CD46 functions as a C3b/C4b-binding glycoprotein that inhibits complement activation on host cells. It also serves as a measles virus receptor, an adherence factor for group A Streptococcus pyogenes, and a cellular pilus receptor for pathogenic Neisseria.

• Specifications:

  Flow cytometry: 1-2ug/million cells, Immunofluorescence: 1-2 µg/mL

• UniProt:

  P15529

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  Recombinant human CD46 protein was used as the immunogen for the CD46 antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgG2a κ

• Clone:

  197-2B1

• Applications:

  FACS, IF

• Purity:

  Protein affinity

• Format:

  Purified

• Buffer:

  0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

• Reconstitution:

  Aliquot the CD46 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This CD46 antibody is available for research use only.

• Storage Conditions:

  Aliquot the CD46 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation:

  0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide

• Applications Notes:

  Optimal dilution of the CD46 antibody should be determined by the researcher.

• CAS Number:

  9007-83-4

• Location:

  Cell Surface