Recombinant CD44 Antibody

• Description :

  CD44 is an adhesion molecule, which binds hyaluronic acid and participates in a number of cell-cell interactions, including lymphocyte homing.CD44 is expressed on approximately 90% of lymphocytes, monocytes, granulocytes, and, in lower amounts on thymocytes, fibroblasts, and erythrocytes. The expression of specific cell adhesion molecule CD44 splice variants has been reported to be associated with metastasis in certain human malignancies.

• CAS Number :

  9000-83-3

• Specifications :

  Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 minutes at RT

• UniProt :

  P16070

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  A portion of amino acids 150-250 from the human protein was used as the immunogen for the recombinant CD44 antibody.

• Clonality :

  Recombinant Monoclonal

• Isotype :

  IgG κ

• Clone :

  HCAM/4110R

• Type :

  Recombinant

• Applications :

  IHC-P

• Purity :

  Protein A affinity chromatography

• Format :

  Purified

• Buffer :

  1 mg/ml in 1X PBS; BSA free, sodium azide free

• Reconstitution :

  Store the recombinant CD44 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

• Limitations :

  This recombinant CD44 antibody is available for research use only.

• Storage Conditions :

  Store the recombinant CD44 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

• Formulation :

  1 mg/mL in 1X PBS; BSA free, sodium azide free

• Applications Notes :

  Optimal dilution of the recombinant CD44 antibody should be determined by the researcher.

• Location :

  Cell surface

• Image Legend :

  IHC staining of FFPE human tonsil with recombinant CD44 antibody (clone HCAM/4110R) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min followed by cooling at RT for 20 min.