Products for Research Use Only

B7-H6 Antibody

CAT: 0800-V8734SAF-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-V8734SAF-100UGSize:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
B7-H6 (NCR3LG1) is a transmembrane endogenous ligand expressed on the surfaces of tumor cells. B7-H6 binds with NKp30 present on NK cells. Binding of B7-H6 to NKp30 causes the ligation of NKp30 subsequently inducing NK cell activation and target cell cytolysis. B7-H6 is not constitutively expressed on normal tissue. Whether it can be expressed endogenously under certain conditions is under investigation. B7-H6 has been detected on circulating pro-inflammatory CD14 (+) CD16 (+) monocytes in some patients with sepsis.
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 minutes at RT
UniProt
Q68D85
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 38-169 from the human protein was used as the immunogen for the B7-H6 antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
B7H6/4821
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Store the B7-H6 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This B7-H6 antibody is available for research use only.
Storage Conditions
Store the B7-H6 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Optimal dilution of the B7-H6 antibody should be determined by the researcher.
Image Legend
IHC staining of FFPE human tonsil with B7-H6 antibody. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.

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