B7-H3 Antibody / CD276

• Description:

  May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. [UniProt]

• Specifications:

  Western blot: 1-3 µg/mL, ELISA (peptide) LOD: 1:8000

• UniProt:

  Q5ZPR3

• Host:

  Goat

• Reactivity:

  Human

• Immunogen:

  Amino acids KHSDSKEDDGQE were used as the immunogen for this B7-H3 antibody.

• Clonality:

  Polyclonal

• Isotype:

  Ig

• Applications:

  WB, ELISA (peptide)

• Purity:

  Antigen affinity

• Format:

  Antigen affinity purified

• Buffer:

  0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide

• Reconstitution:

  Aliquot and store the B7-H3 antibody at -20oC.

• Limitations:

  This B7-H3 antibody is available for research use only.

• Storage Conditions:

  Aliquot and store the B7-H3 antibody at -20°C.

• Formulation:

  0.5 mg/mL in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide

• Applications Notes:

  Optimal dilution of the B7-H3 antibody should be determined by the researcher.

• CAS Number:

  9007-83-4

• Image Legend:

  Western blot testing of human 1) placenta and 2) testis lysate with B7-H3 antibody at 0.1 and 2 ug/ml, respectively. Expected molecular weight: 57-110 kDa depending on level of glycosylation.