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B7-H3 Antibody / CD276

CAT: 0800-R36471-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R36471-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. [UniProt]
CAS Number
9007-83-4
Specifications
Western blot: 1-3 µg/mL, ELISA (peptide) LOD: 1:8000
UniProt
Q5ZPR3
Host
Goat
Reactivity
Human
Immunogen
Amino acids KHSDSKEDDGQE were used as the immunogen for this B7-H3 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA (peptide)
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide
Reconstitution
Aliquot and store the B7-H3 antibody at -20oC.
Limitations
This B7-H3 antibody is available for research use only.
Storage Conditions
Aliquot and store the B7-H3 antibody at -20°C.
Formulation
0.5 mg/mL in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide
Applications Notes
Optimal dilution of the B7-H3 antibody should be determined by the researcher.
Image Legend
Western blot testing of human 1) placenta and 2) testis lysate with B7-H3 antibody at 0.1 and 2 ug/ml, respectively. Expected molecular weight: 57-110 kDa depending on level of glycosylation.

UniProtKB · Q5ZPR3

CD276 antigen

CD276_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q5ZPR3
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CD276
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
Q6P5Y4, Q6UXI2, Q8NBI8, Q8NC34, Q8NCB6, Q9BXR1
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

PTM

Disulfide bondGlycoproteinPhosphoprotein

Domain

Immunoglobulin domainRepeatSignalTransmembraneTransmembrane helix

Cellular component

Membrane

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