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Periostin Antibody / POSTN

CAT: 0800-V8697SAF-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-V8697SAF-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Periostin (PN, POSTN), also designated osteoblast-specific factor 2 (OSF-2), is a disulfide linked protein originally isolated as a osteoblast-specific factor. Periostin is a secreted protein that binds heparin and functions as a ligand for 1) . Periostin contains a typical signal sequence, followed by a cysteine-rich domain, a fourfold repeated domain, which shows homology with the insect protein fasciclin, and a C-terminal domain.
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 minutes at RT
UniProt
Q15063
Host
Mouse
Reactivity
Human
Immunogen
Recombinant full-length human protein was used as the immunogen for the Periostin antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
POSTN/3503
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Store the Periostin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This Periostin antibody is available for research use only.
Storage Conditions
Store the Periostin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Optimal dilution of the Periostin antibody should be determined by the researcher.
Location
Secreted, cytoplasm
Image Legend
IHC staining of FFPE human colon carcinoma with Periostin antibody (clone POSTN/3503) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.

UniProtKB · Q15063

Periostin

POSTN_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q15063
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
POSTN
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
PN
EC number
—
Processing
Precursor
Secondary accessions
B1ALD8, B1ALD9, C0IMJ1, C0IMJ2, C0IMJ4, D2KRH7, F5H628, Q15064, Q29XZ0, Q3KPJ5, Q5VSY5, Q8IZF9
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

Cell adhesion

PTM

Disulfide bondGamma-carboxyglutamic acidGlycoprotein

Cellular component

Extracellular matrixGolgi apparatusSecreted

Molecular function

Heparin-binding

Domain

RepeatSignal

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