Recombinant Integrin alpha E Antibody / CD103

CAT: 0800-V8419SAF-100UGSize: 100 µgDry Ice: NoHazardous: No
CAT#:0800-V8419SAF-100UGSize:100 µg
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Description
This MAb recognizes a protein of 150kDa, identified as CD103, which is the alpha-E integrin subunit of the heterodimeric alpha-E beta-7 (aEb7) integrin belonging to a small beta-7 integrin subfamily. CD103 is expressed on more than 95% of intraepithelial CD8+ cells and on 40% of mucosa-associated T cells, whereas less than 2% of resting blood lymphocytes are CD103-positive. In several malignant conditions, such as T-cell lymphomas and hairy cell leukemia (HCL), the cells express CD103. Antibody to CD103 is an extremely useful addition to the IHC panel for the diagnosis of hairy cell leukemia (HCL) .
CAS Number
9000-83-3
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 minutes at RT
UniProt
P38570
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human ITGAE partial protein was used as the immunogen for the Integrin alpha E antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG
Clone
ITGAE/3904R
Type
Recombinant
Applications
IHC-P
Purity
Protein A affinity chromatography
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Store the recombinant Integrin alpha E antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This recombinant Integrin alpha E antibody is available for research use only.
Storage Conditions
Store the recombinant Integrin alpha E antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Optimal dilution of the recombinant Integrin alpha E antibody should be determined by the researcher.
Location
Cell surface and cytoplasm
Image Legend
IHC staining of FFPE human tonsil with recombinant Integrin alpha E antibody (clone ITGAE/3904R) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.

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