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ITGB1 Antibody / CD29

CAT: 0800-V8418-20UGSize: 20 µgDry Ice: NoHazardous: No
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CAT#:0800-V8418-20UGSize:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CD29/Integrin beta 1/ITGB1 is an adhesion receptor and co-stimulatory molecule. This antigen was initially characterized as GPIIa on platelets and as the common b1 subunit of the very late antigen (VLA) protein family. CD29 forms a non-covalent heterodimeric complex with integrin alpha subunits. It also mediates adhesion to invasion and thrombospondin.
CAS Number
9007-83-4
Specifications
ELISA: order Ab without BSA for coating, Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 minutes at RT
UniProt
P05556
Host
Mouse
Reactivity
Human
Immunogen
Purified human beta 1 integrin from HT1080 fibrosarcoma cells was used as the immunogen for the ITGB1 antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
ITGB1/3613
Applications
ELISA, IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the ITGB1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This ITGB1 antibody is available for research use only.
Storage Conditions
Store the ITGB1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the ITGB1 antibody should be determined by the researcher.
Location
Cell membrane, cytoplasm
Image Legend
IHC staining of FFPE human kidney with ITGB1 antibody. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.

UniProtKB · P05556

Integrin beta-1

ITB1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P05556
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ITGB1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
A8K6N2, D3DRX9, D3DRY3, D3DRY4, D3DRY5, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647, Q29RW2, Q7Z3V1, Q8WUM6
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationDisulfide bondGlycoproteinIsopeptide bondPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicing

Ligand

CalciumMagnesiumMetal-binding

Biological process

Cell adhesionHost-virus interactionMyogenesis

Cellular component

Cell junctionCell membraneCell projectionEndosomeMembrane

Domain

EGF-like domainRepeatSignalTransmembraneTransmembrane helix

Molecular function

Host cell receptor for virus entryIntegrinReceptor

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