Integrin beta 1 Antibody / ITGB1 / CD29

• Description:

  Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. Integrins link the actin cytoskeleton with the extracellular matrix and they transmit signals bidirectionally between the extracellular matrix and cytoplasmic domains. Beta-integrins are primarily responsible for targeting integrin dimers to the appropriate subcellular locations, which in adhesive cells is mainly focal adhesions. Integrin beta-1 mutants lose the ability to target to sites of focal adhesions. [Wiki]

• Specifications:

  Western blot: 1:1000

• UniProt:

  P05556

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  Purified His-tagged protein was used to produced this monoclonal Integrin beta 1 antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgG1

• Clone:

  1084CT17.4.1

• Applications:

  WB, ELISA

• Purity:

  Purified

• Format:

  Purified

• Buffer:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Reconstitution:

  Store at 4oC for up to one month. For long term, aliquot the Integrin beta 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This Integrin beta 1 antibody is available for research use only.

• Storage Conditions:

  Store at 4°C for up to one month. For long term, aliquot the Integrin beta 1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes:

  The stated application concentrations are suggested starting amounts. Titration of the Integrin beta 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• CAS Number:

  9007-83-4

• Image Legend:

  Integrin beta 1 antibody western blot analysis in U87-MG lysate. Predicted molecular weight: 88/130~150 kDa (unmodified/glycosylated) .