CD28 Antibody

• Description:

  Recognizes a glycoprotein of 44-88kDa, which is identified as CD28. It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.

• Specifications:

  ELISA (order BSA-free format for coating)

• UniProt:

  P10747

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  Recombinant human CD28 protein was used as the immunogen for the CD28 antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgG1 k

• Clone:

  C28/74

• Applications:

  ELISA

• Purity:

  Protein G affinity chromatography

• Format:

  Purified

• Buffer:

  1 mg/ml in 1X PBS; BSA free, sodium azide free

• Reconstitution:

  Store the CD28 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

• Limitations:

  This CD28 antibody is available for research use only.

• Storage Conditions:

  Store the CD28 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

• Formulation:

  1 mg/mL in 1X PBS; BSA free, sodium azide free

• Applications Notes:

  Optimal dilution of the CD28 antibody should be determined by the researcher.

• CAS Number:

  9007-83-4

• Image Legend:

  SDS-PAGE analysis of purified, BSA-free CD28 antibody (clone C28/74) as confirmation of integrity and purity.