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Recombinant SOX9 Antibody

CAT: 0800-V8091-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-V8091-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Sox genes comprise a family of genes that are related to the mammalian sex-determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. SOX9 plays an important role in the normal skeletal development. It may regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes.
CAS Number
9000-83-3
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
P48436
Host
Rabbit
Reactivity
Human
Immunogen
A recombinant human partial protein (amino acids 393-508) was used as the immunogen for the recombinant SOX9 antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG κ
Clone
SOX9/3141R
Type
Recombinant
Applications
IHC-P
Purity
Protein A affinity chromatography
Format
Purified
Buffer
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the recombinant SOX9 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This recombinant SOX9 antibody is available for research use only.
Storage Conditions
Store the recombinant SOX9 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the recombinant SOX9 antibody should be determined by the researcher.
Location
Nuclear
Image Legend
IHC staining of FFPE human pancreas with recombinant SOX9 antibody (clone SOX9/3141R) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min followed by cooling at RT for 20 min.

UniProtKB · P48436

Transcription factor SOX-9

SOX9_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P48436
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SOX9
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q53Y80
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Molecular function

ActivatorDNA-binding

Biological process

DifferentiationTranscriptionTranscription regulation

Disease

Disease variant

Cellular component

Nucleus

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