c-Myc Recombinant Antibody

c-Myc Recombinant Antibody

• Description: It recognizes a transcription factor of 64-67kDa, identified as c-myc. Its epitope spans between aa 410-419 (EQKLISEEDL) which is a specific portion of an alpha helical region of human c-myc protein. This MAb shows no cross-reaction with v-myc. c-myc is involved in the control of cell proliferation and differentiation and is amplified and/or overexpressed in a variety of tumors. Over-expression of c-myc protein occurs frequently in luminal cells of prostate intraepithelial neoplasia as well as in most primary carcinomas and metastatic disease.
• CAS Number: 9000-83-3
• UniProt: P01106
• Host: Rabbit
• Immunogen: Amino acids 408-439 were used as the immunogen for the recombinant c-Myc antibody. The specific epitope has been localized to amino acids 410-419 (EQKLISEEDL).
• Clonality: Monoclonal
• Isotype: IgG κ
• Type: Recombinant
• Applications: ELISA, FACS
• Format: Purified
• Buffer: 0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
• Reconstitution: Store the recombinant c-Myc antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
• Limitations: This recombinant c-Myc antibody is available for research use only.