LMO2 Antibody / Rhombotin 2

• Description:

  The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. It has a particular function in normal and lymphatic endothelial cells involving the regulation of angiogenesis and lymph-angiogenesis. Immunohistochemical studies have also demonstrated expression of LMO2 in both normal germinal center B-cells and germinal center-derived B-cell lymphomas, including follicular lymphoma and diffuse large B-cell lymphoma.The use of anti-LMO2 is valuable as a tool in the identification of lymphomas of B-cell origin. LMO2 is useful in differentiating follicular lymphoma (LMO2+) from nodal marginal zone lymphoma (LM02-). It also is positive in Hodgkin s and Burkitt s lymphomas.

• UniProt:

  P25791

• Host:

  Mouse

• Immunogen:

  A recombinant human partial protein (amino acids 23-140) was used as the immunogen for the LMO2 antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgG2b κ

• Applications:

  FACS, WB, IHC-P

• Format:

  Purified

• Buffer:

  0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

• Reconstitution:

  Store the LMO2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

• Limitations:

  This LMO2 antibody is available for research use only.

• CAS Number:

  9007-83-4