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GATA3 Antibody

CAT: 0800-V7806-20UGSize: 20 µgDry Ice: NoHazardous: No
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CAT#:0800-V7806-20UGSize:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GATA-3 is a zinc finger transcription factor and plays an important role in promoting and directing cell proliferation, development, and differentiation in many tissues and cell types. GATA-3 expression is primarily seen in breast and urothelial carcinomas.'Therefore, GATA3 antibody can be useful in the identification of unknown primary carcinoma when carcinomas of the breast or bladder are a possibility.
CAS Number
9007-83-4
Specifications
ELISA (order BSA-free format for coating), Flow cytometry: 1-2ug/10^6 cells in 0.1ml, Western blot: 1-2 µg/mL
UniProt
P23771
Host
Mouse
Reactivity
Human
Immunogen
A recombinant human partial protein (amino acids 357-436) was used as the immunogen for the GATA3 antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
GATA3/2445
Applications
ELISA, FACS, WB
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the GATA3 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This GATA3 antibody is available for research use only.
Storage Conditions
Store the GATA3 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the GATA3 antibody should be determined by the researcher.
Location
Nuclear
Image Legend
Analysis of HuProt (TM) microarray containing more than 19,000 full-length human proteins using GATA3 antibody (clone GATA3/2445) . These results demonstrate the foremost specificity of the GATA3/2445 mAb. Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt (TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt (TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.

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