ETS1 Antibody

• Description :

  ETS1 proto-oncogene is an important transcription factor that plays a role in cell proliferation and differentiation. ETS1 is related to the growth of carcinoma cells by its regulation of the transcription of matrix metalloproteinases and urokinase-type plasminogen activator.The processes of tumor invasion and metastasis depend on the increased proteolytic activity of the invading tumor cells that may involve matrix metalloproteinases, cathepsins B and D and plasminogen activator in the metastatic cascade. ETS1 is preferentially expressed in lymphoid cells, where it is essential for the maintenance of the normal pool of resting T and B cells.ETS1 expression level and distribution are differentially controlled in resting, activated and apoptotic lymphocytes.

• Specifications :

  ELISA (order BSA-free format for coating)

• UniProt :

  P14921

• Host :

  Mouse

• Reactivity :

  Human

• Immunogen :

  A recombinant human partial protein (amino acids 137-230) was used as the immunogen for the ETS1 antibody.

• Clonality :

  Monoclonal

• Isotype :

  IgG2b κ

• Clone :

  ETS1/1801

• Applications :

  ELISA

• Purity :

  Protein G affinity chromatography

• Format :

  Purified

• Buffer :

  1 mg/ml in 1X PBS; BSA free, sodium azide free

• Reconstitution :

  Store the ETS1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

• Limitations :

  This ETS1 antibody is available for research use only.

• Storage Conditions :

  Store the ETS1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

• Formulation :

  1 mg/mL in 1X PBS; BSA free, sodium azide free

• Applications Notes :

  Optimal dilution of the ETS1 antibody should be determined by the researcher.

• CAS Number :

  9007-83-4