DNMT1 Antibody

CAT: 0800-V7716SAF-100UGSize: 100 µgDry Ice: NoHazardous: No
CAT#:0800-V7716SAF-100UGSize:100 µg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE.
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
P26358
Host
Mouse
Reactivity
Human
Immunogen
Amino acids 767-912 from the human protein was used as the immunogen for the DNMT1 antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
DNMT1/2061
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Store the DNMT1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This DNMT1 antibody is available for research use only.
Storage Conditions
Store the DNMT1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Optimal dilution of the DNMT1 antibody should be determined by the researcher.
Location
Nuclear
Image Legend
IHC staining of FFPE human tonsil with DNMT1 antibody. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min and allow to cool before testing.
Product Datasheet
Loading...

Related Products

CatalogName
RQ7268DNA methyltransferase 1 Antibody / Dnmt1
F40544-0.4MLDnmt2 Antibody
F40544-0.08MLDnmt2 Antibody
F40791-0.4MLDnmt2 Antibody
F40791-0.08MLDnmt2 Antibody
RQ4209Dynamin 1 Antibody / DNM1
FY12215Dnmt2 Antibody / DNA methyltransferase 2 / TRDMT1
RZ1219Zebrafish Dnm1 Antibody / Dnm1a / Dnm1b / Dynamin
RQ4624NONO Antibody / p54nrb Antibody
F53954-0.05MLAntibody

Alternative Products

CatalogName
MBS7127068-01DNMT1 Antibody

Popular Products