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Creatine kinase B Antibody

CAT: 0800-V7681-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-V7681-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Creatine kinases (CK) are a large family of isoenzymes that regulate levels of ATP in subcellular compartments, where they provide ATP at sites of fluctuating energy demand by the transfer of phosphates between creatine and adenine nucleotides. CKs provide the energy of phosphate hydrolysis necessary to drive the normal function of many cellular systems. In cells, the cytosolic CK enzymes consist of two subunits, which can be either B (brain type) or M (muscle type) . There are three different isoenzymes: CKMM, CKBB and CKMB. This MAb recognizes the CKBB isoenzyme and does not react with the B subunit in CKMB.
CAS Number
9007-83-4
Specifications
ELISA (order BSA-free format for coating)
UniProt
P12277
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human full-length protein was used as the immunogen for the Creatine kinase B antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
CKB/1268
Applications
ELISA
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the Creatine kinase B antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This Creatine kinase B antibody is available for research use only.
Storage Conditions
Store the Creatine kinase B antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the Creatine kinase B antibody should be determined by the researcher.
Location
Cytoplasmic

UniProtKB · P12277

Creatine kinase B-type

KCRB_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P12277
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CKB
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.3.2
Processing
—
Secondary accessions
A8K236, B2R5R4, Q2LE07, Q6FG40, Q9UC66
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Ligand

ATP-bindingNucleotide-binding

Cellular component

Cell membraneCytoplasmMembraneMitochondrion

PTM

Isopeptide bondNitrationPhosphoproteinUbl conjugation

Molecular function

KinaseTransferase

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