Products for Research Use Only
RegisterLogin

CD8a Antibody

CAT: 0800-V7612SAF-100UGSize: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-V7612SAF-100UGSize:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
CD8 is a cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha/beta) or as a homodimer (CD8 alpha/alpha) . A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class 1 and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells. For mature T-cells, CD4 and CD8 are mutually exclusive, so anti-CD8, generally used in conjunction with anti-CD4. It is a useful marker for distinguishing helper/inducer T-lymphocytes, and most peripheral T-cell lymphomas are CD4+/CD8-. Anaplastic large cell lymphoma is usually CD4+ and CD8-, and in T-lymphoblastic lymphoma/leukemia, CD4 and CD8 are often co-expressed. CD8 is also found in littoral cell angioma of the spleen.
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
P01732
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human CD8a protein was used as the immunogen for the CD8a antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
IHC-P
Purity
Protein A affinity chromatography
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Store the CD8a antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This CD8a antibody is available for research use only.
Storage Conditions
Store the CD8a antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Optimal dilution of the CD8a antibody should be determined by the researcher.
Location
Cell surface
Image Legend
IHC analysis of FFPE human lymphoma with CD8a antibody . Staining of formalin-fixed tissues requires boiling tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min followed by cooling at RT for 20 min.

Related Products

CatalogName
R30434CD80 Antibody
V3485-20UGCD81 Antibody
R34234-100UGCD80 Antibody
F48980-0.4MLCD80 Antibody
V2056-20UGCD86 Antibody
V8881-100UGCD8B Antibody
V8523SAF-100UGCD86 Antibody
V7498-100UGCD80 Antibody
F54421-0.4MLCD82 Antibody
R30465CD86 Antibody

Alternative Products

CatalogName
10R-CD8AFCKPCD8a antibody

Popular Products