Products for Research Use Only
RegisterLogin

CD23 Antibody

CAT: 0800-V7565BTNSize: 500 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-V7565BTNSize:500 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
CD23 (FCE2) is a type II integral membrane glycoprotein that is expressed on mature B cells, monocytes, eosinophils, platelets and dendritic cells. CD23 is a low affinity IgE receptor that mediates IgE-dependent cytotoxicity and phagocytosis by macrophages and eosinophils. CD23 associates as an oligomer where cooperative binding of at least two lectin domains is required for high affinity IgE binding to CD23. It may play a role in antigen presentation by B cells by interacting with CD40. CD23 has been shown to be associated with the Fyn tyrosine kinase. The truncated molecule can be secreted, then function as a potent mitogenic growth factor. CD23 is expressed on a subpopulation of peripheral blood cells, B-lymphocytes and on EBV transformed B lymphoblastoid cell lines. CD23 is also detected in neoplastic cells from cases of B cell chronic lymphocytic leukemia and some cases on centroblastic/centrocytic lymphoma.
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 2-4 µg/mL for 30 minutes at RT
UniProt
P06734
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 48-321 from the human protein was used as the immunogen for the CD23 antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
FCER2/3592
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Biotin Conjugate
Buffer
0.1 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the CD23 antibody at 2-8oC (up to one month) or aliquot and store at -20oC (longer term).
Limitations
This CD23 antibody is available for research use only.
Storage Conditions
Store the CD23 antibody at 2-8°C (up to one month) or aliquot and store at -20°C (longer term) .
Formulation
0.1 mg/mL with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the CD23 antibody should be determined by the researcher.
Location
Cell surface
Image Legend
IHC staining of FFPE human tonsil with biotin-labeled CD23 antibody (clone FCER2/3592) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
Product Datasheet
Loading...

Related Products

CatalogName
V5437-20UGRecombinant FCER2 Antibody / CD23
V5437-100UGRecombinant FCER2 Antibody / CD23
V5437SAF-100UGRecombinant FCER2 Antibody / CD23
V9456SAF-100UGCD20 Antibody
V8725-100UGCD27 Antibody
V2986-20UGCD27 Antibody
V4166-20UGCD20 Antibody
V4233-20UGCD27 Antibody
V2048CF488-100TCD20 Antibody
V4779-20UGCD21 Antibody

Alternative Products

CatalogName
V0021-01CD23 (ABT-CD23) Antibody
MBS9510626-01Anti-CD23 Antibody [ABT-CD23]
GWB-6FD6A6CD23 Antibody
GWB-8F150FCD23, Antibody

Popular Products