Products for Research Use Only
RegisterLogin

Recombinant pS2 Antibody / TFF1

CAT: 0800-V7460-100UGSize: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-V7460-100UGSize:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
It recognizes a polypeptide of 6.5kDa, identified as pS2 estrogen-regulated protein. pS2 is a trefoil peptide. Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intra-chain disulfide bonds, forming the trefoil motif, or P-domain. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. About 60% of breast carcinomas are positive for pS2. Staining is cytoplasmic, often with localization to the Golgi apparatus. It is shown to be localized in normal stomach mucosa, gastric fluid, goblet cells in the colon and small intestine, and in ulcerations of the gastrointestinal tract. Several studies have shown that pS2 is primarily expressed in estrogen receptor-positive breast tumors and it may define a subset of estrogen-dependent tumors that displays an increased likelihood of response to endocrine therapy.
CAS Number
9000-83-3
Specifications
Immunohistochemistry (FFPE) : 0.5-1 µg/mL for 30 min at RT
UniProt
P04155
Host
Rabbit
Reactivity
Human
Immunogen
Amino acids CFDDTVRGVPWCFYPNTIDVPPEEECEF were used as the immunogen for this recombinant pS2 antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG κ
Clone
TFF1/2969R
Type
Recombinant
Applications
IHC-P
Purity
Protein A affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the recombinant pS2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This recombinant pS2 antibody is available for research use only.
Storage Conditions
Store the recombinant pS2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Location
Cytoplasmic, secreted
Image Legend
IHC staining of FFPE human stomach carcinoma with recombinant pS2 antibody (clone TFF1/2969R) . HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min and allow to cool before testing.

Related Products

CatalogName
V7354IHC-7MLPS2 Antibody / TFF1
V9082IHC-7MLPS2 Antibody / TFF1
V9082SAF-100UGPS2 Antibody / TFF1
V7354-20UGPS2 Antibody / TFF1
V7354-100UGPS2 Antibody / TFF1
V9082-20UGPS2 Antibody / TFF1
V7354SAF-100UGPS2 Antibody / TFF1
R32898PS2 Antibody / Tff1
V9082-100UGPS2 Antibody / TFF1
V4406-100UGRecombinant pS2 Antibody / Estrogen Inducible Protein pS2 / TFF1

Alternative Products

CatalogName
RAC08381-01TFF1 Recombinant Monoclonal Antibody
GTR18574802Recombinant pS2 Antibody / TFF1
AN303532L-01Recombinant TFF1/pS2 Monoclonal Antibody
GTR18317407-01Recombinant Estrogen Inducible Protein pS2 Antibody / TFF1
GTR18572024-01Recombinant TFF1 Antibody / Estrogen Inducible Protein pS2
GTR18317409-01Recombinant pS2 Antibody / Estrogen Inducible Protein pS2 / TFF1
P7194-5μgRecombinant Human TFF1
OPCD07336-50UGTFF1 Recombinant Protein
P5681-01Recombinant Mouse Tff1
4893-100TFF1, human recombinant

Popular Products