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RBP Antibody

CAT: 0800-V7143IHC-7MLSize: 7 mLDry Ice: NoHazardous: No
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CAT#:0800-V7143IHC-7MLSize:7 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Recognizes a protein of 21kDa-25kDa, identified as retinol binding protein-1 (RBP1) . This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein post-transnationally and results in defective delivery and supply to the epidermal cells.
CAS Number
9007-83-4
Specifications
The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
UniProt
P09455
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human Retinol binding protein-1 was used as the immunogen for the RBP antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
RLBD1
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*
Reconstitution
Store the RBP antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This RBP antibody is available for research use only.
Storage Conditions
Store the RBP antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05% sodium azide; *For IHC use only*
Location
Cytoplasmic
Image Legend
IHC testing of FFPE human hepatocellular carcinoma with RBP (clone RLBD1) . Staining of formalin-fixed tissues requires boiling tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min followed by cooling at RT for 20 min.
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