RBP4 Antibody

CAT: 0800-V8707-20UGSize: 20 µgDry Ice: NoHazardous: No
CAT#:0800-V8707-20UGSize:20 µg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Retinol (Vitamin A) is transported in the blood bound to its carrier protein, retinol-binding protein (RBP), also designated plasma retinol-binding protein (PRBP) or RBP4. A member of the lipocalin family, RBP conveys retinol from stores in the liver to peripheral tissues. In plasma, RBP binds transthyretin (TTR, formerly called prealbumin) to prevent glomerular filtration of low molecular weight RBP in the kidneys. The stability of this complex holds diagnostic importance because the molar ratio of RBP:TTR provides an indirect way to indicate marginal Vitamin A deficiency. Vitamin A deficiency blocks the secretion of RBP, resulting in defective delivery and supply to epidermal cells. Originally identified solely as a transporter protein, recent studies correlating increased levels of RBP expression in adipose tissue with Insulin resistance have generated research into the possible roles the protein may play in the pathogenesis of type 2 diabetes and obesity.
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 minutes at RT
UniProt
P02753
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 29-148 from the human protein was used as the immunogen for the RBP4 antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
RBP4/4316
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the RBP4 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This RBP4 antibody is available for research use only.
Storage Conditions
Store the RBP4 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the RBP4 antibody should be determined by the researcher.
Location
Cytoplasmic
Image Legend
IHC staining of FFPE human kidney with RBP4 antibody. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
Product Datasheet
Loading...

Related Products

CatalogName
V4111SAF-100UGRetinol Binding Protein 4 Antibody / RBP4
V8702-100UGRetinol Binding Protein 4 Antibody / RBP4
V8703-20UGRetinol Binding Protein 4 Antibody / RBP4
V8702-20UGRetinol Binding Protein 4 Antibody / RBP4
V4111-100UGRetinol Binding Protein 4 Antibody / RBP4
V8703-100UGRetinol Binding Protein 4 Antibody / RBP4
V4111-20UGRetinol Binding Protein 4 Antibody / RBP4
V8703SAF-100UGRetinol Binding Protein 4 Antibody / RBP4
V8702SAF-100UGRetinol Binding Protein 4 Antibody / RBP4
V9568-100UGRecombinant Retinol Binding Protein 4 Antibody / RBP4

Alternative Products

CatalogName
3716-100RBP4 Antibody

Popular Products