Products for Research Use Only
RegisterLogin

EMI-1 Antibody

CAT: 0800-V7090IHC-7MLSize: 7 mLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-V7090IHC-7MLSize:7 mL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Early Mitotic Inhibitor-1 regulates mitosis by inhibiting the anaphase promoting complex/cyclosome (APC) . It is a conserved F box protein containing a zinc-binding region essential for APC inhibition. The protein functions to promote cyclin A accumulation and S phase entry in somatic cells by inhibiting the APC complex. At the G1-S transition, EMI-1 is transcriptionally induced by the E2F transcription factor. Overexpression accelerates S-phase entry and can override a G1 block caused by overexpression of Cdh1 or the E2F-inhibitor p105 retinoblastoma protein (pRb) . Depleting cells of EMI-1 through RNA interference prevents accumulation of cyclin A and inhibits S phase entry.
CAS Number
9007-83-4
Specifications
The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
UniProt
Q9UKT4
Host
Mouse
Reactivity
Human
Immunogen
A human partial recombinant N-terminal protein fragment was used as the immunogen for the EMI-1 antibody.
Clonality
Monoclonal
Isotype
IgG2a κ
Clone
FBXP5
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*
Reconstitution
Store the EMI-1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This EMI-1 antibody is available for research use only.
Storage Conditions
Store the EMI-1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05% sodium azide; *For IHC use only*
Location
Nuclear
Image Legend
IHC testing of FFPE human ovarian carcinoma and EMI-1 antibody (clone FBXP5) . Staining of formalin-fixed tissues requires boiling tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min followed by cooling at RT for 20 min.
Product Datasheet
Loading...

Related Products

CatalogName
V2527-100UGEMI1 Antibody
V2527SAF-100UGEMI1 Antibody
V2527IHC-7MLEMI1 Antibody
V2527-20UGEMI1 Antibody
V5550SAF-100UGNKX2.1 Antibody / TTF-1
F40894-0.4MLTTF-1 Antibody / NKX2.1
V5551-100UGTTF-1 Antibody / NKX2.1
V5549-100UGNKX2.1 Antibody / TTF-1
F55080-0.05MLSyncytin 1 Antibody / ERVW-1
F55080-0.2MLSyncytin 1 Antibody / ERVW-1

Alternative Products

CatalogName
GTR18574026EMI-1 Antibody
33-932EMI-1 Antibody [FBXP5]
abx027432-01EMI Domain-Containing Protein 1 (EMID1) Antibody
abx215146-01EMI Domain-Containing Protein 2 (EMID2) Antibody
MBL170Mouse Anti-Human IgM (EMI-43) Monoclonal Antibody
GTR180271691.1 Antibody
abx201032-01NK-1.1 Antibody
MBS7159994ctsa-1.1 Antibody
GTR17965027Wee-1.1 Antibody
GTR17962755Arf-1.1 Antibody

Popular Products