Products for Research Use Only
RegisterLogin

P27Kip1 Antibody

CAT: 0800-V7048IHC-7MLSize: 7 mLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-V7048IHC-7MLSize:7 mL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
This mAb recognizes a 27kDa protein, identified as the p27Kip1, a cell cycle regulatory mitotic inhibitor. It is highly specific and shows no cross-reaction with other related mitotic inhibitors. p27Kip1 functions as a negative regulator of G1 progression and has been proposed to function as a possible mediator of TGF- induced G1 arrest. p27Kip1 is a candidate tumor suppressor gene.
CAS Number
9007-83-4
Specifications
The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
UniProt
P46527
Host
Mouse
Reactivity
Human, Mouse and Rat
Immunogen
Recombinant human protein was used as the immunogen for the p27Kip1 antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
KIP27-1
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*
Reconstitution
Store the p27Kip1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This p27Kip1 antibody is available for research use only.
Storage Conditions
Store the p27Kip1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05% sodium azide; *For IHC use only*
Location
Nuclear
Image Legend
IHC testing of FFPE human prostate cancer and p27Kip1 antibody (clone KIP27-1) . Staining of formalin-fixed tissues requires boiling tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min followed by cooling at RT for 20 min.

UniProtKB · P46527

Cyclin-dependent kinase inhibitor 1B

CDN1B_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P46527
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CDKN1B
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q16307, Q5U0H2, Q9BUS6
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Biological process

Cell cycle

Cellular component

CytoplasmEndosomeNucleus

PTM

PhosphoproteinUbl conjugation

Molecular function

Protein kinase inhibitor

Disease

Tumor suppressor

Related Products

CatalogName
V5645SAF-100UGRecombinant CDKN1B Antibody / p27Kip1
V5554-20UGRecombinant p27 Antibody / p27Kip1
V5554-100UGRecombinant p27 Antibody / p27Kip1
V5554SAF-100UGRecombinant p27 Antibody / p27Kip1
V5645-100UGRecombinant CDKN1B Antibody / p27Kip1
V5645-20UGRecombinant CDKN1B Antibody / p27Kip1
V2436CF488-100TP27K1 Antibody
V2086CF488-100TP27K1 Antibody
RQ4624NONO Antibody / p54nrb Antibody
F53954-0.2MLAntibody

Alternative Products

CatalogName
GWB-FA39A5p27Kip1, Antibody
20R-2050p27Kip1 antibody

Popular Products