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GATA3 Antibody

CAT: 0800-V3995IHC-7MLSize: 7 mLDry Ice: NoHazardous: No
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CAT#:0800-V3995IHC-7MLSize:7 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GATA3 is a zinc finger transcription factor and plays an important role in promoting and directing cell proliferation, development, and differentiation in many tissues and cell types. GATA3 expression is primarily seen in breast and urothelial carcinomas. Therefore, GATA3 antibody can be useful in the identification of unknown primary carcinoma when carcinomas of the breast or bladder are a possibility.
CAS Number
9007-83-4
Specifications
The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
UniProt
P23771
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 357-463 from the human protein were used as the immunogen for this GATA3 antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
GATA3/2442
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*
Reconstitution
Store the GATA3 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This GATA3 antibody is available for research use only.
Storage Conditions
Store the GATA3 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05% sodium azide; *For IHC use only*
Location
Nuclear
Image Legend
IHC testing of FFPE human breast carcinoma with GATA3 antibody. Required HIER: boil tissue sections in 10mM citrate buffer, pH 6, for 10-20 min and allow to cool prior to testing.
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