CD40 Antibody

CAT: 0800-V3895-100UGSize: 100 µgDry Ice: NoHazardous: No
CAT#:0800-V3895-100UGSize:100 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cluster of differentiation 40, CD40 is a costimulatory protein found on antigen presenting cells and is required for their activation. The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects. [Wiki]
CAS Number
9007-83-4
Specifications
Flow cytometry: 1-2ug/10^6 cells, Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT
UniProt
P25942
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 29-107 from the human protein was used as the immunogen for the CD40 antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
CDLA40-1
Applications
IHC-P, FACS
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the CD40 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This CD40 antibody is available for research use only.
Storage Conditions
Store the CD40 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
The stated application concentrations are suggested starting points. Titration of the CD40 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Cell surface, cytoplasmic
Image Legend
IHC testing of human tonsil with CD40 antibody (clone CDLA40-1) . Required HIER: boil tissue sections in 10mM citrate buffer, pH 6, for 10-20 min.

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