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TROP2 Antibody / TACSTD2

CAT: 0800-V3851BTNSize: 500 µLDry Ice: NoHazardous: No
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CAT#:0800-V3851BTNSize:500 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TACSTD2is a cell surface glycoprotein receptor. It is a single pass type I membrane protein containing one thyroglobulin type-1 domain, an epidermal growth factor-like repeat, a phosphatidylinositol binding site and tyrosine phosphorylation sites near the C-terminus. It plays a role intransducing intracellular calcium signals. It is expressed in trophoblast cells, cornea and multi-stratified epithelia. It is also highly expressed in several types of tumors and is involved in regulating the growth of carcinoma cells.
CAS Number
9007-83-4
Specifications
Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 minutes at RT
UniProt
P09758
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 31-274 from the human protein was used as the immunogen for the TROP2 antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
TACSTD2/2151
Applications
WB, IHC-P
Purity
Protein G affinity chromatography
Format
Biotin Conjugate
Buffer
0.1 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the TROP2 antibody at 2-8oC (up to one month) or aliquot and store at -20oC (longer term).
Limitations
This TROP2 antibody is available for research use only.
Storage Conditions
Store the TROP2 antibody at 2-8°C (up to one month) or aliquot and store at -20°C (longer term) .
Formulation
0.1 mg/mL with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the TROP2 antibody should be determined by the researcher.
Location
Cytoplasmic
Image Legend
IHC testing of FFPE human pancreatic carcinoma with biotinylated TROP2 antibody (clone TACSTD2/2151) . Required HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min followed by cooling at RT for 20 min.
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