Products for Research Use Only
RegisterLogin

Recombinant vWF Antibody

CAT: 0800-V3491-100UGSize: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-V3491-100UGSize:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposi's sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.
CAS Number
9000-83-3
Specifications
Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT
UniProt
P04275
Host
Rabbit
Reactivity
Human
Immunogen
Amino acids 1815-1939 from the human protein were used as the immunogen for this recombinant vWF antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG κ
Clone
VWF/1859R
Type
Recombinant
Applications
WB, IHC-P
Purity
Protein A affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the recombinant vWF antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This recombinant vWF antibody is available for research use only.
Storage Conditions
Store the recombinant vWF antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Location
Cytoplasmic
Image Legend
IHC testing of FFPE human tonsil with recombinant vWF antibody (clone VWF/1859R) . Required HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min followed by cooling at RT for 20 min.

UniProtKB · P04275

von Willebrand factor

VWF_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P04275
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
VWF
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
vWF
EC number
—
Processing
Precursor
Secondary accessions
Q8TCE8, Q99806
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

Blood coagulationCell adhesionHemostasis

PTM

Cleavage on pair of basic residuesDisulfide bondGlycoprotein

Disease

Disease variantvon Willebrand disease

Cellular component

Extracellular matrixSecreted

Domain

RepeatSignal

Related Products

CatalogName
F52535-0.4MLVWF Antibody
V3417-100UGVWF Antibody
V3417-20UGVWF Antibody
V3417SAF-100UGVWF Antibody
V3418-100UGVWF Antibody
V3418-20UGVWF Antibody
R31491VWF Antibody
F52535-0.08MLVWF Antibody
V3418SAF-100UGVWF Antibody
V2929-20UGAnti-vWF Antibody

Alternative Products

CatalogName
RC-16121-01Recombinant WAS Antibody
RN-14606-01Recombinant HMCES Antibody
RC-15096-01Recombinant STUB1 Antibody
RC-4566-01Recombinant HLA-A Antibody
PT-A04714-01Recombinant VEGF Antibody
bsm-62255R-01HOXB4 Recombinant Antibody
bsm-62247R-01FHIT Recombinant Antibody
bsm-62236R-01KIF4A Recombinant Antibody
bsm-62223R-01UBR5 Recombinant Antibody
bsm-62213R-01MBNL1 Recombinant Antibody

Popular Products