HPV-16 E6 Antibody

CAT: 0800-V3488-20UGSize: 20 µgDry Ice: NoHazardous: No
CAT#:0800-V3488-20UGSize:20 µg
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Description
Reacts with E6 protein of human papilloma virus type 16 (HPV-16) . Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies. The antibody reacts very strongly with formalin-fixed, paraffin-embedded tissues containing HPV-16.
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT
UniProt
Not Known
Host
Mouse
Reactivity
HPV-16
Immunogen
HPV-16 E6 peptide (MHQKRTAMFQDPPQERPRKLPQLC) was used as the immunogen for the HPV-16 E6 antibody.
Clonality
Monoclonal
Isotype
IgG2a κ
Clone
HPV16/1296
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the HPV-16 E6 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This HPV-16 E6 antibody is available for research use only.
Storage Conditions
Store the HPV-16 E6 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the HPV-16 E6 antibody should be determined by the researcher.
Location
Nuclear
Image Legend
IHC testing of FFPE human cervix with HPV-16 E6 antibody (clone HPV16/1296) . Required HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min followed by cooling at RT for 20 min.

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