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PD1 Antibody

CAT: 0800-V3384SAF-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-V3384SAF-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PDCD1 (Programmed cell death-1 protein), also called PD1 and CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD1 is expressed by few B-cells, so may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma.
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT
UniProt
Q15116
Host
Rabbit
Reactivity
Human
Immunogen
A full-length human protein was used as the immunogen for the PD1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
IHC-P
Purity
Protein A affinity chromatography
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Store the PD1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This PD1 antibody is available for research use only.
Storage Conditions
Store the PD1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Titering of the PD1 antibody may be required for optimal performance.
Location
Cell surface & cytoplasmic
Image Legend
IHC testing of FFPE human tonsil with PD1 antibody. Required HIER: steam sections in 10mM Tris with 1mM EDTA, pH 9, for 10-20 min.

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