Lambda Light Chain Antibody

CAT: 0800-V3262-20UGSize: 20 µgDry Ice: NoHazardous: No
CAT#:0800-V3262-20UGSize:20 µg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
This mAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with kappa light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 0.1-0.2 µg/mL for 30 min at RT
UniProt
P01701, P01842
Host
Mouse
Reactivity
Human
Immunogen
Purified human lambda light chain was used as the immunogen for this Lambda Light Chain antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
LLC/1738
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the Lambda Light Chain antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This Lambda Light Chain antibody is available for research use only.
Storage Conditions
Store the Lambda Light Chain antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
The optimal dilution of the Lambda Light Chain antibody for each application should be determined by the researcher.
Location
Cell Surface, Cytoplasmic and Secreted
Image Legend
IHC testing of FFPE human tonsil stained with Lambda Light Chain antibody (clone LLC/1738) . Required HIER: boil tissue sections in 10mM citrate buffer, pH 6, for 10-20 min.

Related Products

CatalogName
V5396-20UGRecombinant IGL Antibody / Lambda Light Chain
V5747-20UGIGLV1-51 Antibody / Lambda Light Chain
V5747-100UGIGLV1-51 Antibody / Lambda Light Chain
V5396SAF-100UGRecombinant IGL Antibody / Lambda Light Chain
V5747SAF-100UGIGLV1-51 Antibody / Lambda Light Chain
V5396-100UGRecombinant IGL Antibody / Lambda Light Chain
V3353-100UGFerritin Light Chain Antibody
V3135-100UGKappa Light Chain Antibody
V7122-20UGNeurofilament Antibody (light chain)
V3300SAF-100UGClathrin Light Chain Antibody

Alternative Products

CatalogName
CR388-1mlLambda light chain

Popular Products