Basic Cytokeratin Antibody

• Description :

  This mAb recognizes basic (Type II or HMW) cytokeratins, which include 67kDa (CK1) ; 64kDa (CK3) ; 59kDa (CK4) ; 58kDa (CK5) ; 56kDa (CK6) ; 52kDa (CK8) . Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50 , 48, 46, 45, and 40kDa. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.

• Specifications :

  Immunohistochemistry (FFPE) : 0.1-0.2 µg/mL for 30 min at RT

• UniProt :

  Q01546

• Host :

  Mouse

• Reactivity :

  Human, Rat

• Immunogen :

  Recombinant human KRT76 protein was used as the immunogen for the Basic Cytokeratin antibody.

• Clonality :

  Monoclonal

• Isotype :

  IgG1 k

• Clone :

  KRTH/1076

• Applications :

  IHC-P

• Purity :

  Protein G affinity chromatography

• Format :

  Purified

• Buffer :

  1 mg/ml in 1X PBS; BSA free, sodium azide free

• Reconstitution :

  Store the Basic Cytokeratin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

• Limitations :

  This Basic Cytokeratin antibody is available for research use only.

• Storage Conditions :

  Store the Basic Cytokeratin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

• Formulation :

  1 mg/mL in 1X PBS; BSA free, sodium azide free

• CAS Number :

  9007-83-4

• Location :

  Cytoplasmic

• Image Legend :

  IHC: Formalin paraffin human skin stained with Basic Cytokeratin antibody (KRTH/1076) .