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CD70 Antibody

CAT: 0800-V3033-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-V3033-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CD70 belongs to the tumor necrosis factor (TNF) ligand family. It is a cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.
CAS Number
9007-83-4
Specifications
Flow cytometry: 1-2ug/million cells, Immunofluorescence: 1-3 µg/mL, Immunohistochemistry: 1-2 µg/mL for 30 min at RT
UniProt
P32970
Host
Mouse
Reactivity
Human
Immunogen
The human WM-1 (Waldenstrom s macroglobulinemia) cell line was used as the immunogen for the CD70 antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
BU69
Applications
FACS, IF, IHC
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the CD70 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This CD70 antibody is available for research use only.
Storage Conditions
Store the CD70 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the CD70 antibody should be determined by the researcher.1. This mAb blocks the interaction between CD27 and CD70, and has been shown to inhibit T cell proliferation induced by dendritic cells.
Location
Cell surface
Image Legend
SDS-PAGE analysis of purified, BSA-free CD70 antibody (clone BU69) as confirmation of integrity and purity.

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