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PECAM Antibody

CAT: 0800-V2781S-0.5MLSize: 0.5 mLDry Ice: NoHazardous: No
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CAT#:0800-V2781S-0.5MLSize:0.5 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 mAb reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence.
CAS Number
9007-83-4
Specifications
Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 1:50-1:100 for 30 min at RT
UniProt
P16284
Host
Mouse
Reactivity
Human
Immunogen
Prokaryotic recombinant fusion protein corresponding to a portion of the extracellular domain downstream of the signal sequence of CD31/PECAM was used as the immunogen for the PECAM antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
1A10
Applications
WB, IHC-P
Purity
Unpurified high titer supernatant
Format
Bioreactor concentrate
Buffer
Bioreactor concentrate with 0.05% sodium azide
Reconstitution
Store the PECAM antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This PECAM antibody is available for research use only.
Storage Conditions
Store the PECAM antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
Bioreactor concentrate with 0.05% sodium azide
Location
Cell surface and cytoplasm of endothelial cells
Image Legend
IHC: Formalin-fixed, paraffin-embedded human tonsil stained with PECAM antibody (1A10)

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