PECAM Antibody

CAT: 0013-GTR18081472-01Size: 0.1 mLDry Ice: NoHazardous: No

1 / 1

CAT#:0013-GTR18081472-01Size:0.1 mL

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 mAb reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence.

UniProt

P16284

Reactivity

Human

Immunogen

Prokaryotic recombinant fusion protein corresponding to a portion of the extracellular domain downstream of the signal sequence of CD31/PECAM was used as the immunogen for the PECAM antibody.

Clonality

Monoclonal

Clone

1A10

Conjugation

Unconjugated

Field of Research

Immunology & Inflammation

Purification

Unpurified high titer supernatant

Dilution

Western blot: 1-2ug/ml, Immunohistochemistry (FFPE) : 1:50-1:100 for 30 min at RT

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

Optimal dilution of the PECAM antibody should be determined by the researcher.1. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 min2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Tested Applications

IHC-P, WB

Host or Source

Mouse

Preservative

Bioreactor concentrate with 0.05% sodium azide

Isotype

Mouse IgG1, kappa

Related Products

Catalog	Name
GTR18196650-01	PECAM-1 Antibody
GTR18196137-01	PECAM-1 Antibody
GTR18193162-01	PECAM-1 Antibody
GTR18193160-01	PECAM-1 Antibody
GTR18193159-01	PECAM-1 Antibody
GTR18406490-01	PECAM-1 Antibody
GTR18405807-01	PECAM-1 Antibody
GTR18405367-01	PECAM-1 Antibody
GTR18405359-01	PECAM-1 Antibody
GTR18194600-01	PECAM-1 Antibody

Alternative Products

Catalog	Name
V2781S-0.1ML	PECAM Antibody
MBS9510006-01	PECAM-1 Antibody
48124-01	CD31/PECAM Antibody
GWB-86D2B6	PECAM-1 (CD31), Antibody
V4531SAF-100UG	CD31 Antibody / PECAM-1
V2780PE-100T	PECAM Antibody PE Conjugate
403501-01	PECAM-1

PECAM Antibody

Related Products

Alternative Products

Popular Products